The World Health Oganisation (WHO) opened the Decade of Action for Road Safety 2021-2030 in Geneva, with the ambitious target of preventing at least 50% of road traffic deaths and injuries by 2030. WHO and the UN Regional Commissions, in cooperation with other partners in the UN Road Safety Collaboration, have developed a Global Plan for the Decade of Action. Road traffic accidents have remained a major cause of death globally, even though every one of those deaths and injuries is preventable.   A Global Plan has been developed to support the implementation of the Decade of Action and its objectives.