The European Commission with the active contribution of NTUA, SWOV and KFV has published at the European Road Safety Observatory, the Powered Two-Wheelers Thematic Report which refers to the safety of moped riders and motorcyclists as vulnerable road users. This Thematic Report describes how PTWs participate in traffic, as well as PTWs in relation to road safety hazards. Moreover, countermeasures regarding safer road users, vehicles and roads are suggested.