Dimosthenis Pavlou has successfully defended his PhD dissertation titled: Traffic and safety behaviour of drivers with neurological diseases affecting cognitive functions. This PhD thesis was carried out at the Department of Transportation Planning and Engineering at the School of Civil Engineering of the National Technical University of Athens under the supervision of Prof. George Yannis. The impact of brain pathologies on reaction time, accident probability, driving errors, and driving performance was under investigation. The driving behaviour was examined in terms of both traffic and safety behaviour and the neurological diseases affecting cognitive functions concerned Alzheimer’s disease (AD), Parkinson’s disease (PD), and Mild Cognitive Impairment (MCI). A large-scale driving simulator experiment was carried out, comprising a medical/neurological and neuropsychological assessment of 225 drivers, and a set of driving tasks for different scenarios. An innovative statistical analysis methodology has been developed and implemented, based on Regression Models, Principal Component Analysis and Structural Equation Models.