A  paper titled “Economic Assessment of Road Infrastructure Safety Schemes in Greece Using Crash Prediction Methodology”, authored by G. Yannis, A. Dragomanovits, J. Roussou, D. Nikolaou, was presented at the Transportation Research Board (TRB) 99th Annual Meeting, on January 2020.  This research presents a case study for the economic assessment of road safety schemes in crash prone locations in selected rural highways in Greece, using crash prediction models from the AASHTO Highway Safety Manual. The analysis results demonstrate the high impact of this large Road Safety Scheme.