The European Commission published the road fatalities collision matrix in urban roads in the EU. The available EU-wide data for 2022 contained in the CARE database, demonstrate that 38% of road traffic fatalities occured in urban areas, with vulnerable road users (pedestrians, cyclists and users of powered two-wheelers) representing almost 70% of total fatalities. This collision matrix shows clearly that urban road user fatalities occur overwhelmingly when a crash involves cars and vulnerable road users, underlining the need to improve protection of these vulnerable road users. Furthermore, the high number (31% of the total crashes) of single vehicle crashes of cars and two-wheelers demosntrate the critical role of speeding in the cities.