The scientific journal Sustainability organised with great success the publication of a special issue under the theme: “Challenges and Strategies for Sustainable Transportation and Traffic Safety”. Topics of interest include, but are not limited to Traffic safety impact assessment of sustainability measures, Cost-Benefit effects of sustainable safety interventions and Policies for the integration of the dimension of sustainability in traffic safety interventions. Guest editors of this special issue were Athanasios Theofilatos, Apostolos Ziakopoulos and Ioanna Pagoni.